Combined proton and photon conformal radiotherapy for intracranial atypical and malignant Meningioma. The main casebooks website contains the digital edition and critical introduction, but one website was not enough. Reprints and Permissions. There were two cases of acute grade III toxicity: One case of severe ulcerating mucositis requiring hospitalization and one case of prolonged nausea due to intracranial pressure requiring the administration of corticosteroids. In total, four patients showed local progression. A holder of fellowships at the Center for Human Values at Princeton and the Netherlands Institute of Advanced Study, Connolly is the author or editor of three books, over 30 articles, and nearly 40 book reviews. Article Google Scholar For a history of the project, and a long list of acknowledgements that begins with staff at the Wellcome Trust, our generous funders, and the Bodleian Library, which owns the manuscripts, see here. On the second series, the dots represent instances of tuberculosis, typhoid fever, scarlet fever, and diphtheria. The most common symptoms among late toxicity were fatigue and headaches both 9.
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Table 3 Acute and late treatment-related toxicity Full size table. In a separate series focusing exclusively on skull base meningiomas PFS was similar for low-risk histology and Futhermore, patient-reported outcome showed very mild toxicity with no more than 3.
Our dataset is on GitHub. Comput Methods Prog Biomed. For distinguished contributions to understanding the social structure of science and nature of objectivity and how different scientific approaches produce unique descriptive and causal knowledge.
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In an environment of increasing economic and political uncertainty, RESET takes serious challenges such as: How can we anticipate and govern the social, ethical or environmental impacts of scientific and technological change?
(Mannheim); Heiden, M. (Langen); Northoff. Email: (at) Prof. Michael Platten, MD DKFZ, CCU Neuroimmunology & Brain Tumor Immunology (G) and University of.
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Notably, the results of McDonald et al. The BHA is published online. Kessel et al. The most common among worsening symptoms after RT were headaches 8. Potential role of intensity-modulated photons and protons in the treatment of the breast and regional nodes.
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|For descriptive baseline analyses, continous variables are given as means SD and median quartiles, range where appropriate and categorical variables as absolute and relative frequencies.
None of those deaths was meningioma-related.
Methods Patient characteristics and histology In the present analysis we included consecutive patients with meningiomas of the skull base that had not previously received radiotherapy. If you have any questions, please email reset mcts.
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Symptoms were controlled after endocrinologic follow-up and adequate medication. Particle radiotherapy could be performed safely without toxicity-related interruptions. Rieken performed data analysis, endpoint evaluation and collaborated on writing the manuscript.
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names unknown, of Friedrich Daniel Bracht, deceased Dr. Ing. Horst-Tonn; Ludwigsburger St. Jürgen Renn, Max Planck Institute for the History of Science (Germany) . Margaret Jacob; Susan D. Jones; Gwen Kay; Daniel Kevles; John Lesch; Albert Lewis Jeff Steck; James Summer; Mary Terrall; Jenna Tonn; Brigitte Van Tiggelen James Grossman, Michele Moody-Adams, Carl Pforzheimer, Elaine Sisman, and.
In the present analysis we included consecutive patients with meningiomas of the skull base that had not previously received radiotherapy.
Among the most common symptoms were focal alopecia Overall survival calculated from beginning of particle therapy for patients with skull base meningiomas treated with particle therapy, regardless of histology. Due to the complex anatomy of the skull base, tumor adherence to bony structures and the close proximity to sensitive organs at risk OARtotal resection is often not possible as it may cause to substantial morbidity. They found a PFS rate after 5 years of Due to the complex structure of the cranial base and its close proximity to critical structures, surgery is often associated with substantial morbidity.
Comparison of radiosurgery treatment modalities based on complication and control probabilities.
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|Acute treatment-related toxicity was mild and mostly resolved within the first 6 months after therapy completion.
None of the patients who died had progressed at the last recorded follow-up. Symptoms were controlled after endocrinologic follow-up and adequate medication. To showcase the contents of full cases — the scope of the project did not extend to transcribing the judgments — we have prepared five hundred fully-transcribed cases and a selective index of interesting things from across the corpus.
There were two cases of acute grade III toxicity: One case of severe ulcerating mucositis requiring hospitalization and one case of prolonged nausea due to intracranial pressure requiring the administration of corticosteroids. No more than 10 patients reported any one symptom as late toxicity. By varying the particle energy, the position of the Bragg peak can be altered.